Thermo Fisher Scientific Calcium Channel beta-4 Polyclonal Antibody
Goat 유래의 Polyclonal 항체로 Human Calcium Channel beta-4 단백질을 인식합니다. Western blot에 0.2–0.6 µg/mL 농도로 사용 가능하며, canine, mouse, rat에서도 반응이 예측됩니다. 액상 형태로 -20°C 보관하며 연구용으로 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–0.6 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (DYPDSYQDTYKPH) corresponding to the internal amino acids of CACNB4 (aa 491–504) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10986600 |
Product Specific Information
- This antibody is predicted to react with canine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:4,000.
Target Information
This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins.
Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio.
The encoded protein modulates G protein inhibition, increases peak calcium current, controls alpha-1 subunit membrane targeting, and shifts voltage dependence of activation and inactivation.
Mutations in this gene have been associated with idiopathic generalized epilepsy and juvenile myoclonic epilepsy.
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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