Thermo Fisher Scientific RDH12 Polyclonal Antibody

Applications

• Western Blot (WB): 0.2–1.0 µg/mL

Product Specifications

Product Specific Information

This target displays homology in the following species:
Cow: 85%; Dog: 92%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Pig: 86%; Rabbit: 85%; Rat: 79%; Yeast: 79%; Zebrafish: 92%

Target Information

The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity.
Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.