Thermo Fisher Scientific CD59 Monoclonal Antibody (MEM-43), FITC
인간 CD59 단백질을 인식하는 FITC 결합 단클론 항체로, Flow Cytometry 분석에 적합합니다. 높은 형광 효율과 수용성을 제공하며, PBS/BSA 용액에 보관됩니다. 4°C 암소 보관, 인체 반응성, 마우스 IgG2a 아이소타입.
- 카탈로그번호
- MHCD5901x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD59 Monoclonal Antibody (MEM-43), FITC
Applications
- Flow Cytometry (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-43 |
| Immunogen | Human CD59 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | PBS with 4 mg/mL BSA |
| Contains | 0.1% Sodium Azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10373827 |
Additional Formats
Product Specific Information
FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility, making them suitable for flow cytometric analysis.
Target Information
CD59 (Protectin) is a small (18–20 kDa) GPI-anchored protein ubiquitously expressed as an inhibitor of the membrane attack complex (MAC). It protects autologous cells from complement-mediated lysis by binding complement components C8 and/or C9, preventing pore formation. CD59 also interacts with CD2, promoting T cell costimulation and signal transduction. Mutations in CD59 can lead to deficiency associated with hemolytic anemia, thrombosis, and cerebral infarction. Multiple alternatively spliced transcript variants exist.
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