Thermo Fisher Scientific ALOX5 Monoclonal Antibody (OTI1D6), TrueMAB
인간 ALOX5 단백질(아미노산 18-364)에 특이적인 Mouse IgG2a 단클론 항체로 Western blot에 사용 가능. 무보존제, 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도. 염증 반응 연구 및 leukotriene 합성 관련 연구에 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 18–364 of human ALOX5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
This gene encodes a protein required for leukotriene synthesis together with Arachidonate 5-lipoxygenase-activating protein. Leukotrienes are arachidonic acid metabolites implicated in various inflammatory responses, including asthma, arthritis, and psoriasis. The protein localizes to the plasma membrane. Inhibitors of its function prevent translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit its activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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