Thermo Fisher Scientific WDR4 Monoclonal Antibody (OTI4G1), TrueMAB

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000

-

Immunocytochemistry (ICC/IF)

1:100

-

Flow Cytometry (Flow)

1:100

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI4G1

Immunogen

Full length human recombinant protein of human WDR4 produced in HEK293T cell. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:WDR4,uniProtId:P57081-1,ncbiNodeId:9606,antigenRange:1-412,antigenLength:412,antigenImageFileName:CF503815_WDR4_P57081-1_House_mouse.svg,antigenImageFileNamePDP:CF503815_WDR4_P57081-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

Required for 7-methylguanosine modification of tRNA. This protein is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD). which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes. including cell cycle progression. signal transduction. apoptosis. and gene regulation. This protein is excluded as a candidate for a form of nonsyndromic deafness (DFNB10). but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternative splicing of this gene generates at least 3 transcript variants. two of which diverge at the 3` UTR and thus encode the same protein products.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.