Thermo Fisher Scientific CX3CR1 Polyclonal Antibody
CX3CR1 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간·마우스·랫트 시료에 반응합니다. WB, IHC(P/F), Flow, ELISA 등 다양한 응용에 적합하며, Protein A 정제 및 1 mg/mL 농도로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CX3CR1, amino acids 151–250 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CX3CR1 is a chemokine receptor required as a coreceptor for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28, CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven-transmembrane protein was identified as the receptor for fractalkine and renamed CX3CR1. CX3CR1 functions as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, inhibited by fractalkine. It mediates leukocyte migration and adhesion and is expressed in various human tissues and cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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