
Thermo Fisher Scientific KCNJ11 Polyclonal Antibody
Thermo Fisher Scientific의 KCNJ11 Polyclonal Antibody는 Human, Mouse, Rat에 반응하는 Rabbit Ig 폴리클로날 항체입니다. WB 및 IHC에 사용 가능하며, N-terminal region의 합성 펩타이드로 면역화되었습니다. 연구용으로 안정적이며 장기 보관 시 -20°C에서 유지됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of mouse KCNJ11 (Kir6.2) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: KCNJ11.
Target Information
This receptor is controlled by G proteins. Inward rectifier potassium channels preferentially allow potassium influx into the cell. Voltage dependence is regulated by extracellular potassium concentration; increased external potassium shifts channel opening to more positive voltages. Inward rectification arises from blockage of outward current by internal magnesium and can be inhibited by extracellular barium.
KCNJ11 is a subunit of ATP-sensitive potassium channels (KATP) and forms cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore, while ABCC9 is required for activation and regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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