Thermo Fisher Scientific Human IFN-omega Recombinant Protein, eBioscience

Applications

ELISA (ELISA)

• Assay-Dependent

Control (Ctrl)

• Assay-Dependent

Miscellaneous PubMed (Misc)

• View 1 publication

Product Specifications

Product Specific Information

In the human genome, the IFN-omega gene family consists of seven members located on chromosome 9. However, only one of these genes is functional, giving rise to the IFN-omega protein, whereas the others are non-functional pseudogenes. The IFN-omega gene is not expressed in unstimulated cells. Viral infection induces expression of the gene, producing an N-glycosylated protein consisting of 172 or 174 amino acids with an apparent molecular mass of about 25 kDa.
A single carbohydrate group consists mainly of biantennary complex oligosaccharides with variable amounts of N-acetyl neuraminic acid. Quantitatively, IFN-omega is a major component of human leukocyte interferon, contributing approximately 10–15% of its total antiviral activity.

• Purity: >95% prior to addition of human serum albumin
• Molecular Weight: 20.0 kDa

Target Information

IFN-omega is a type I interferon induced by virus-infected leukocytes. Members of the type I interferon family, including IFN-alpha, IFN-beta, and IFN-omega, signal through the IFNAR-1/IFNAR-2 receptor complex and exhibit antiviral and antiproliferative activities.
IFN-omega shares approximately 75% sequence homology with IFN-alpha and contains two conserved disulfide bonds essential for full biological activity.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.