Thermo Fisher Scientific INO80 Polyclonal Antibody
Thermo Fisher Scientific의 INO80 Polyclonal Antibody는 인간 INO80 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 4°C에서 보관합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1506 and 1556 of human INO80 homolog |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
Target Information
DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex, involved in transcriptional regulation, DNA replication, and DNA repair. According to PubMed:20687897, its role in DNA double-strand break repair is largely indirect through transcriptional regulation.
Recruited by YY1 to YY1-activated genes as an essential coactivator. Binds DNA and exhibits double-stranded DNA-dependent ATPase activity in vitro.
Participates in UV-damage excision repair, DNA replication, and chromosome segregation during the cell division cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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