Thermo Fisher Scientific APC5 Polyclonal Antibody
인간 ANAPC5 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 단기 4°C 보관 및 장기 -20°C 보관이 권장됩니다.
- 카탈로그번호
- PA583478
- 판매단위
- pk
카탈로그
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ANAPC5. Recombinant protein control fragment (Product #RP-104708). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790631 |
Product Specific Information
Immunogen sequence:
ADGAILDKGR AMFLVAKCQV ASAASYDQPK KAEALEAAIE NLNEAKNYFA KVDCKERIRD VVYFQARLYH TLGKTQERNR CAMLFRQLHQ ELPS
Target Information
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation. The encoded protein is essential for APC/C ubiquitination function and its interaction with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been identified, resulting in shorter protein isoforms due to translation initiation at downstream AUG sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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