Thermo Fisher Scientific HSP27 Polyclonal Antibody
Western blot에 최적화된 Rabbit Polyclonal HSP27 항체로 인간, 생쥐, 랫트 반응성이 있음. 정제된 액상 형태로 PBS(pH 7.2) 및 1% BSA 포함. 세포 스트레스 반응 및 단백질 폴딩 연구에 적합. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length human HSP27 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 1% BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536323 |
Target Information
In response to environmental stress, cells increase expression of heat shock proteins (HSPs). HSPB1 (also known as HSP27) is a small heat shock protein acting as a molecular chaperone to maintain denatured proteins in a folding-competent state. It contributes to stress resistance and actin organization. HSP27 regulates phosphorylation and axonal transport of neurofilament proteins. Mutations in the gene are associated with Charcot-Marie-Tooth disease 2F and distal hereditary motor neuronopathy type 2B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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