Thermo Fisher Scientific TFEB Recombinant Rabbit Monoclonal Antibody (HL1065)
TFEB 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot에 최적화됨. HEK293 세포에서 발현되며 Protein A로 정제된 고순도 항체. 인간 TFEB의 N-말단 서열 기반 면역원 사용. 연구용으로만 사용 가능하며 -20°C 이하에서 장기 보관.
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Thermo Fisher Scientific TFEB Recombinant Rabbit Monoclonal Antibody (HL1065)
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000–1:10,000
Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL1065 |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human TFEB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911526 |
Product Specific Information
Store as concentrated solution. Centrifuge briefly prior to opening vial.
For short-term storage (1–2 weeks), store at 4°C.
For long-term storage, aliquot and store at -20°C or below.
Avoid multiple freeze-thaw cycles.
Target Information
The Transcription Factor EB (TFEB) is a member of the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors.
Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1.
Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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