Thermo Fisher Scientific C3orf75 Polyclonal Antibody
Human C3orf75 단백질을 인식하는 Rabbit Polyclonal 항체로, ICC/IF 분석에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보존됩니다. RNA polymerase II elongator complex 연구용으로 권장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human C3orf75. Recombinant protein control fragment (Product #RP-107342) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2663188 |
Product Specific Information
Immunogen sequence:
LGVSLTMARER GQLVFLEGLK SAVDVVFQAQ KEPHPLQFLR EANAGNLKPL FEFVREALKP VDSGEAR
Highest antigen sequence identity to the following orthologs:
- Mouse: 68%
- Rat: 72%
Target Information
C3orf75 is a component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, involved in transcriptional elongation (PubMed:22854966).
The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:29332244) and is involved in cell migration.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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