Thermo Fisher Scientific CD200R3 Monoclonal Antibody (Ba13), Alexa Fluor 647, eBioscience

Applications

• Flow Cytometry (Flow): Tested at 0.25 µg/test

Product Specifications

Additional Formats

• Alexa Fluor 488
• PE
• PE-Cyanine7
• Request custom conjugation

Product Specific Information

Description:
Ba13 monoclonal antibody recognizes mouse CD200R3, a surface receptor expressed by basophils and mast cells.

Applications Reported:
Reported for use in flow cytometric analysis.

Applications Tested:
Tested by flow cytometric analysis of MC/9 cell line. Recommended ≤0.25 µg per test (100 µL final volume). Cell number should be determined empirically (10^5–10^8 cells/test). Antibody should be titrated for optimal performance.

Fluorescence Parameters:

• Excitation: 633–647 nm
• Emission: 668 nm
• Laser: Red Laser

Target Information

CD200R3 (also known as CD200RLb) is a dimeric cell surface receptor containing two Ig-like extracellular domains, belonging to the immunoglobulin superfamily.
The intracellular region associates with adaptor molecules DAP12, and possibly DAP10, CD3 zeta, and FcR gamma-chain, enabling stimulatory signaling.
CD200R3 is similar to activatory receptors CD200R2 and CD200R4, unlike inhibitory receptor CD200R1.
Primarily expressed by basophils and mast cells, involved in anti-parasitic and allergic responses.
Surface expression decreases rapidly upon activation (within 30 minutes).
Unlike CD200R, CD200R3 does not bind CD200.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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