Thermo Fisher Scientific hnRNP H3 Polyclonal Antibody
Rabbit polyclonal antibody against human hnRNP H3, validated for WB and IHC applications. Recognizes N-terminal region (aa 51-100) with high sequence conservation across species. Supplied as liquid, 1 mg/mL in PBS with 2% sucrose. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 4–8 µg/mL |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human HNRPH3 (aa 51–100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608964 |
Product Specific Information
PA5-41837 detects HNRPH3 in WB and IHC applications.
Peptide sequence:
DYQGRSTGEA FVQFASKEIA ENALGKHKER IGHRYIEIFR SSRSEIKGFY
Sequence homology:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Target Information
HNRPH3 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These are RNA-binding proteins that complex with heterogeneous nuclear RNA (hnRNA). They are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing, mRNA metabolism, and transport.
While all hnRNPs are present in the nucleus, some shuttle between the nucleus and cytoplasm. HNRPH3 contains two quasi-RRM domains that bind RNA and is localized in nuclear bodies. It participates in splicing and early heat shock-induced splicing arrest by transiently leaving hnRNP complexes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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