Thermo Fisher Scientific ANKMY2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human ANKMY2 N-terminal region. Validated for Western blot applications. High specificity and homology across multiple species. Supplied in liquid form with PBS and sucrose, stored at -20°C.
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Applications
- Western Blot (WB): 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human ANKMY2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689221 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 92%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Yeast: 90%
Target Information
ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito, and Caenorhabditis elegans.
Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicates that ANKMY2 may play a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, divert differentiation to an alternative fate, and promote pre-leukaemic states.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-70311_ANKMY2_Q8IV38-1_Rabbit.svg, PA5-70311_ANKMY2_Q8IV38-1_Rabbit_PDP.jpeg)
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