Thermo Fisher Scientific Cathepsin K Polyclonal Antibody
Rabbit Polyclonal 항체로 Human Cathepsin K를 인식하며, Western blot과 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제된 Lyophilized 형태로 제공. 골 재형성과 종양 침윤 관련 연구에 적합. 연구용 전용 제품.
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- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived human Cathepsin K recombinant protein (Position: A115–M329) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746215 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. It belongs to the peptidase C1 protein family and is predominantly expressed in osteoclasts. This protein is also expressed in a significant fraction of human breast cancers, potentially contributing to tumor invasiveness. Mutations in this gene cause pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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