Thermo Fisher Scientific PRKD3 Polyclonal Antibody
PRKD3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 고순도 친화 크로마토그래피 정제, PBS 기반 버퍼에 보존. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PRKD3 (Accession O94806), corresponding to amino acid residues A25–I75 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850408 |
Product Specific Information
Antibody detects endogenous levels of total PRKD3.
Target Information
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are involved in diverse cellular signaling pathways. They also serve as major receptors for phorbol esters, a class of tumor promoters.
Each PKC family member has a specific expression profile and distinct functional roles. The protein encoded by this gene is one of the PKC family members, rapidly activated by agonists of G protein-coupled receptors. It is found in both cytoplasm and nucleus, with nuclear accumulation enhanced upon activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, requiring intact phospholipase C gamma and other PKC family members.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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