Thermo Fisher Scientific UGGT1 Polyclonal Antibody
UGGT1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 인간 및 돼지 반응성. Protein A 정제, PBS/glycerol 버퍼, 4°C 또는 -20°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific UGGT1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Pig |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human UGGT1 protein, Leu1221–Leu1536 (Accession #Q9NYU2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091396 |
Target Information
UDP-glucose:glycoprotein glucosyltransferase (UGGT) is a 170 kDa lumenal endoplasmic reticulum (ER) resident protein that catalyzes monoglucosylation of high mannose oligosaccharides. UGGT catalyzes the transfer of glucose from UDP-glucose to Man7-9GlcNAc2 moiety of unfolded glycoproteins in a Ca²⁺ dependent reaction. It binds unfolded glycoproteins via two substrate elements: a N-acetylglucosamine unit on the oligosaccharide and hydrophobic amino acids exposed in the denatured conformation. UGGT is thought to act as a sensor distinguishing folded from denatured proteins in the ER.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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