Thermo Fisher Scientific RNF14 Recombinant Rabbit Monoclonal Antibody (23GB4610)
RNF14 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도 친화 크로마토그래피 정제 및 안정한 PBS/glycerol buffer에 보관됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB4610 |
| Immunogen | A synthesized peptide derived from human RNF14 (350–375 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The protein encoded by this gene contains a RING zinc finger motif involved in protein–protein interactions. It interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate tissue. A dominant negative mutant has been shown to inhibit AR-mediated prostate cancer growth. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin ligase (E3) for certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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