Thermo Fisher Scientific WIPI1 Monoclonal Antibody (OTI8F9), TrueMAB
WIPI1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 최적화되어 있습니다. E. coli에서 생산된 인간 WIPI1(aa 195-446) 재조합 단백질을 면역원으로 사용했습니다. 액상 형태로 1 mg/mL 농도이며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8F9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 195–446 of human WIPI1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18, or WIPI49, is thought to play a role in autophagy and may regulate protein trafficking in certain recycling pathways.
It contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins.
WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles, and the trans-Golgi network.
It is ubiquitously expressed with highest expression in heart, testis, placenta, pancreas, and skeletal muscle.
WIPI1 is upregulated in a variety of tumors, suggesting a role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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