Thermo Fisher Scientific ASAP1 Polyclonal Antibody
ASAP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Mouse 및 Rat 시료에 반응하며 Western Blot에 적합. 단백질 A로 정제된 액상 항체로, 0.5 mg/mL 농도. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
- Western Blot (WB): 2.0–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Within the range of amino acids 962–999 of mouse ASAP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540847 |
Target Information
ASAP1, also known as Development and differentiation enhancing factor 1, is a protein with two ANK repeats, an Arf-GAP domain, a PH domain, and a SH3 domain. ASAP1 forms homodimers and interacts with SRC and CRK. Its activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2). It exhibits GTPase-activating protein activity for ARF1 and ARF5, and lesser activity toward ARF6. ASAP1 is involved in coordinating membrane trafficking with cell growth or actin cytoskeleton remodeling through interactions with SRC and PIP2. It may function as a signal transduction protein in fibroblast differentiation into adipocytes and possibly other cell types. ASAP1 is widely expressed across tissues and is identified as a proto-oncogene associated with invasive breast cancer and other malignant tumors such as uveal melanomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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