Thermo Fisher Scientific Complement C4 Monoclonal Antibody (KT29)
인간 Complement C4 단백질을 인식하는 Mouse IgG1 단클론 항체로 ELISA에 적합. Protein A로 정제된 액상 형태이며 1 mg/mL 농도. 냉장(2–8°C) 보관, 장기 보관 시 -20°C 권장. 연구용으로만 사용.
- 카탈로그번호
- MA172520
- 판매단위
- pk
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Applications
- ELISA
Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KT29 |
| Immunogen | Human C4 purified from blood |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_923305 |
Target Information
This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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