Thermo Fisher Scientific Complement C4 Monoclonal Antibody (KT29)

Applications

Tested Dilution

Publications

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

KT29

Immunogen

Human C4 purified from blood. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Complement C4,uniProtId:P0C0L4-1,ncbiNodeId:9606,antigenRange:1-1744,antigenLength:1744,antigenImageFileName:MA1-72520_Complement_C4_P0C0L4-1_House_mouse.svg,antigenImageFileNamePDP:MA1-72520_Complement_C4_P0C0L4-1_House_mouse_PDP.jpeg,sortOrder:1},{targetFamily:Complement C4,uniProtId:P0C0L5-1,ncbiNodeId:9606,antigenRange:1-1744,antigenLength:1744,antigenImageFileName:MA1-72520_Complement_C4_P0C0L5-1_House_mouse.svg,antigenImageFileNamePDP:MA1-72520_Complement_C4_P0C0L5-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.09% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_923305

Target Information

This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.