Thermo Fisher Scientific COPS6 Monoclonal Antibody (OTI4E7)
COPS6 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone OTI4E7). Western blot, IHC, ICC/IF에 사용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적이며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 58–327 of COPS6 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723005 |
Target Information
The protein encoded by the COPS6 gene is one of the eight subunits of the COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways.
The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of the 26S proteasome.
COP9 signalosome interacts with SCF-type E3 ubiquitin ligases and acts as a positive regulator of these ligases.
This protein belongs to the translation initiation factor 3 superfamily and is involved in cell cycle regulation. It is also likely to serve as a cellular cofactor for the HIV-1 accessory gene product Vpr.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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