Thermo Fisher Scientific SP100 Polyclonal Antibody
인간 SP100 단백질에 특이적인 Rabbit Polyclonal Antibody로, Western blot과 IHC(Paraffin) 분석에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | — |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SP100. Recombinant protein control fragment (Product #RP-91589) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647754 |
Product Specific Information
Immunogen sequence:
QARTHHNQAS DIIVISSEDS EGSTDVDEPL EVFISAPRSE PVINNDNPLE SNDEKEGQEA TCSRPQIVPE PMDFRKLSTF RESFKKRVIG QDHDFSESSE
Highest antigen sequence identity to the following orthologs:
- Mouse: 24%
- Rat: 26%
Target Information
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies.
PML and SP100 are covalently modified by the SUMO-1 modifier, crucial to nuclear body interactions.
The encoded protein binds heterochromatin proteins and is thought to play roles in tumorigenesis, immunity, and gene regulation.
Alternatively spliced variants have been identified for this gene; one encodes a high-mobility group protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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