Thermo Fisher Scientific TEAD1 Polyclonal Antibody
TEAD1 단백질을 인식하는 Thermo Fisher Scientific의 고품질 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 인간, 마우스, 랫트 반응성. 액상 형태로 -20°C 보관. 연구용으로만 사용.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TEAD1 (Accession P28347), corresponding to amino acid residues R75–M125 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854146 |
Product Specific Information
Antibody detects endogenous levels of total TEAD1.
Target Information
TEF1 (Transcriptional enhancer factor 1), a member of the TEA/ATTS domain family, is a nuclear protein expressed in various cell types and regulates numerous genes.
TEF family members possess a conserved DNA-binding domain. TEF-1 binds to GT-IIC, SphI/II, and M-CAT sequences, and also to the proximal regulatory element (PRE) of transforming growth factor-alpha, which is overexpressed in many cancers.
TEF-1 represses transcription in placental cells and is phosphorylated by several PKC isozymes, reducing its DNA-binding capability. This phosphorylation suggests a role in PKC inhibition.
TEF-1 also interacts with tumor antigen (TAg), implying a potential role in tumorigenesis. Dimerization may be essential for TEF-1’s function as a transcriptional regulator.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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