Thermo Fisher Scientific Transferrin Receptor Monoclonal Antibody (OX-26), FITC
FITC로 결합된 OX-26 클론의 Transferrin Receptor 단클론 항체로 랫트 시료에 반응합니다. Flow Cytometry에 적합하며, 철 수송 관련 세포 표지에 활용됩니다. Protein G로 정제된 액상 형태로 제공되며, 안정적인 형광 특성을 가집니다.
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Thermo Fisher Scientific Transferrin Receptor Monoclonal Antibody (OX-26), FITC
Applications
- Flow Cytometry (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OX-26 |
| Immunogen | PHA activated lymph node cells of a PVG rat |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles). Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538948 |
Additional Formats
- Unconjugated
- Biotin
- Custom conjugation available upon request
Target Information
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release, and the apotransferrin-receptor complex is recycled to the cell surface. Transferrin receptor is essential for erythrocyte and nervous system development. Serum transferrin receptor (sTfR) serves as a biomarker for detecting EPO misuse and diagnosing anemia related to various conditions such as rheumatoid arthritis, pregnancy, irritable bowel syndrome, and HIV.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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