Thermo Fisher Scientific MR1/Major histocompatibility complex, class I-related Monoclonal Antibody (MR1/7578)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2, kappa

Class

Monoclonal

Type

Antibody

Clone

MR1/7578

Immunogen

Recombinant fragment (around aa50-250) of human MR1 protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MR1,uniProtId:Q95460-1,ncbiNodeId:9606,antigenRange:50-250,antigenLength:341,antigenImageFileName:3140-MSM2-P0_MR1_Q95460-1_House_mouse.svg,antigenImageFileNamePDP:3140-MSM2-P0_MR1_Q95460-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive Control: Human kidney placenta or tonsil.

Cellular Location: Secreted. Cell membrane.

Target Information

Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T- cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.