Thermo Fisher Scientific CSE1L Monoclonal Antibody (1C1)
CSE1L 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, ICC/IF, ELISA에 사용 가능. 인간 시료에 반응하며, Affinity chromatography로 정제된 액상 형태. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C1 |
| Immunogen | CSE1L (NP_001307, 872–971 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
LIGLFELPED DTIPDEEHFI DIEDTPGYQT AFSQLAFAGK KEHDPVGQMV NNPKIHLAQS LHKLSTACPG RVPSMVSTSL NAEALQYLQG YLQAARVTLL
Target Information
Proteins carrying a nuclear localization signal (NLS) are imported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha is then returned to the cytoplasm by the combined action of RANBP1 and RANGAP1.
The protein encoded by this gene binds strongly to NLS-free importin-alpha, with binding released in the cytoplasm. It may also play a role in apoptosis and cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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