Thermo Fisher Scientific ATF5 Polyclonal Antibody
Human ATF5 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제된 액상형 제품으로, 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용 가능.
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Thermo Fisher Scientific ATF5 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ATF5 (UniProt ID: Q9Y2D1-1, range 36–161) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790283 |
Product Specific Information
Immunogen sequence:
PLAPYEVLGG ALEGGLPVGG EPLAGDGFSD WMTERVDFTA LLPLEPPLPP GTLPQPSPTP PDLEAMASLL KKELEQMEDF FLDAPPLPPP SPPPLPPPPL PPAPSLPLSL PSFDLPQPPV LDTLDL
Target Information
ATF5 is a protein coding gene functioning as a transcription factor that can either stimulate or repress gene transcription through binding to regulatory elements such as CRE, ARE, and AARE. It plays a critical role in cell survival, proliferation, and differentiation, particularly in cerebral cortex formation and olfactory sensory neuron maintenance. ATF5 activity is modulated by CCND3 and CDK4 and is involved in multiple signaling pathways including SHH and IL1B. It also participates in adipocyte differentiation and centrosome dynamics regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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