Thermo Fisher Scientific HIV2 Nef Monoclonal Antibody (4B5)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

-

Immunoprecipitation (IP)

Assay-Dependent

-

Product Specifications

Species Reactivity

Virus

Host/Isotype

Rat / IgG1

Class

Monoclonal

Type

Antibody

Clone

4B5

Immunogen

TrpE-Fusion protein produced in X63Ag8.653 cells

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2538487

Product Specific Information

MA5-17015 recognizes HIV-2 Nef and does not cross react with HIV-1 Nef.

MA5-17015 has been successfully used in immunoprecipitation and Western blot applications.

The MA5-17015 immunogen is a TrpE-Fusion protein produced in X63Ag8.653 cells.

Target Information

Nef is a multifunctional protein of 27 kDa in HIV-1 and 35 kDa in HIV-2. It induces the endocytosis of CD4 Receptor and reduces the MHC-1 Receptors. Thereby it enhances viral infectivity and affects T-cell signalling.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.