Thermo Fisher Scientific HP1 beta Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Predicted to react with bovine, canine, mouse, and rat based on sequence homology.
• Tested in Peptide ELISA: antibody detection limit dilution 1:32,000.

Target Information

This gene encodes a highly conserved nonhistone protein, a member of the heterochromatin protein family. The protein is enriched in heterochromatin and associated with centromeres.
It contains:

• An N-terminal chromodomain that binds histone proteins via methylated lysine residues
• A C-terminal chromoshadow domain responsible for homodimerization and interaction with chromatin-associated nonhistone proteins

This protein plays an important role in the epigenetic regulation of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants encoding the same protein have been identified.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.