Thermo Fisher Scientific PPP6C Polyclonal Antibody
Rabbit 폴리클로날 항체로 PPP6C 단백질을 인식하며 Western blot 및 Immunoprecipitation에 적합. 인간 단백질 인산화효소 6 촉매 서브유닛의 C-말단 영역(250–305)을 면역원으로 사용. 액상 형태, 1 mg/mL 농도, 4°C 보관, 연구용 전용.
- 카탈로그번호
- A300844Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PPP6C Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 250 and the C-terminus (residue 305) of Human Protein Phosphatase 6, Catalytic Subunit (PPP6C, UniProt ID: O00743-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat
Target Information
Distinct DNA repair pathways minimize the consequences of mutagenic events. Reactive oxygen species (ROS) are highly reactive atoms with an unpaired electron that can cause double-strand DNA breaks. Artemis, named after the Greek goddess for the protection of children, is one of the major proteins contributing to the preservation of double-strand breaks in DNA by cutting away damaged parts, allowing the strands to rejoin.
Artemis is a single-strand-specific 5′ to 3′ exonuclease that forms a complex with the 469 kDa DNA-dependent protein kinase (DNA-PKcs). DNA-PKcs phosphorylates Artemis, granting endonucleolytic activity on 5′ and 3′ overhangs and hairpins. These activities are essential for V(D)J recombination and for the 5′ and 3′ overhang processing in nonhomologous DNA end joining.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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