Thermo Fisher Scientific IL12 p35 Polyclonal Antibody, Biotin
IL12 p35 단백질을 인식하는 Biotin 결합 폴리클로날 항체로, Western blot, ELISA, IP 등 다양한 면역분석에 적합합니다. 인체 및 비인간 영장류 반응성이 있으며, Affinity chromatography로 정제되었습니다. 연구용으로만 사용 가능합니다.
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- IL12P35-BIOTIN
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 210–260 on human IL12P35 subunit protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interleukin 12A (IL-12A) is a signaling cytokine belonging to the Interleukin-6 protein superfamily. The IL-12A alpha chain precursor (35 kDa) forms part of a heterodimeric cytokine, IL-12, with diverse biological activities. IL-12A acts as a growth factor for activated T and NK cells, enhances NK/lymphokine-activated killer cell activity, and stimulates IFN-γ production in PBMCs. It plays a role in the differentiation of Th1 and Th2 cells and in the positive regulation of Stat4 phosphorylation. IL-12A signaling in innate immunity involves nitric oxide synthase 2A. Together with EBI3, IL-12A forms interleukin-35 (IL-35), a cytokine associated with regulatory T cell suppressive activity.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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