
Thermo Fisher Scientific C1QA/Complement C1q A-Chain Monoclonal Antibody (C1QA, 2955)
C1QA 단백질을 인식하는 Thermo Fisher Scientific의 마우스 단클론 항체로, Western blot, IHC(P), Peptide Array에 사용 가능. 단백질 A/G 정제, PBS 용액 형태, 보존제 없음. 인간 시료 반응성, 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C1QA, 2955 |
| Immunogen | Recombinant fragment (around aa 104–237) of human C1QA protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- IHC (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Antigen Retrieval: Heat formalin-fixed tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, then cool at room temperature for 20 minutes.
Target Information
C1q is a sub-component of complement C1. It associates with complement components C1r and C1s, which are essential for the progression of the proteolytic complement cascade.
Deficiency of C1q has been linked to lupus erythematosus and glomerulonephritis.
C1q consists of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region near the N-terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A–C–B on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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