Thermo Fisher Scientific Shaker Polyclonal Antibody
Thermo Fisher Scientific의 Shaker 단백질에 대한 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. Fruit fly와 Human에 반응하며, 항원 친화 크로마토그래피로 정제된 고품질 항체입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Fruit fly, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from N-terminus of Shaker protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Positive control: Shaker over-expressed HEK293
- Cellular location: Membrane
Target Information
The assemblage of specific ion channels and receptors at synaptic sites is crucial for signaling between pre- and post-synaptic cells. DLG (Drosophila discs-large gene) is co-localized with Shaker K1 channels, which are clustered at glutamatergic synapses. DLG-Shaker interactions are required in vivo for shaker clustering at the neuromuscular junction. The channel protein Shaker, which is properly synthesized, glycosylated, folded, assembled, and delivered to the plasma membrane, is very important for potassium channel function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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