Thermo Fisher Scientific NUDT1 Monoclonal Antibody (5F11)
NUDT1 단백질을 인식하는 Thermo Fisher Scientific의 단일클론 항체로, Western blot과 ELISA에 적합합니다. Human 시료에 반응하며, Mouse IgG2a 아이소타입입니다. 고순도 친화 크로마토그래피로 정제되었으며, -20°C에서 보관합니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5F11 |
| Immunogen | NUDT1 (AAH14618, 1 a.a. ~179 a.a) full-length recombinant protein with GST tag (MW of GST tag = 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MSGISPQQMG EPEGSWSGKN PGTMGASRLY TLVLVLQPQR VLLGMKKRGF GAGRWNGFGG KVQEGETIED GARRELQEES GLTVDALHKV GQIVFEFVGE PELMDVHVFC TDSIQGTPVE SDEMRPCWFQ LDQIPFKDMW PDDSYWFPLL LQKKKFHGYF KFQGQDTILD YTLREVDTV
Target Information
Oxygen radicals damage chromosomal DNA causing cell death and inducing mutations. Among the various classes of DNA damage caused by oxygen radicals, an oxidized form of guanine base (8-oxoguanine) appears to be important as it can pair with cytosine and adenine, leading to G:C to T:A transversion mutations.
A significant amount of 8-OxoG is formed in mammalian chromosomal DNA, with most damaged nucleotides excised and excreted in urine. Along with 8-oxoG in DNA, 8-oxo-deoxyguanosine (8-oxo-dGTP) forms in the nucleotide pool during normal metabolism and oxidative stress.
8-oxo-dGTP can be incorporated into DNA during replication, causing mispairing unless repaired. MTH converts 8-oxo-dGTP to the monophosphate form, preventing misincorporation. MTH also recognizes 8-oxo-rGTP, which could incorporate into RNA, leading to missense or nonsense protein production.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific MTHFR Polyclonal Antibody, MaxPab
582,600원
Thermo Fisher Scientific
Thermo Fisher Scientific MTHFR Polyclonal Antibody, MaxPab
518,100원
Thermo Fisher Scientific
Thermo Fisher Scientific NUDT1 Monoclonal Antibody (5F11)
518,100원
Thermo Fisher Scientific
Thermo Fisher Scientific MTHFD1 Polyclonal Antibody, MaxPab
518,100원
Thermo Fisher Scientific
Thermo Fisher Scientific MTF1 Monoclonal Antibody (4A5)
518,100원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|