Thermo Fisher Scientific EPS8L1 Polyclonal Antibody
Human EPS8L1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제된 고품질 항체이며, 액상 형태로 제공. 세포 성장과 분화 연구에 활용 가능.
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Applications
Western Blot (WB)
Immunohistochemistry (Paraffin) (IHC (P))
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human EPS8L1. Recombinant protein control fragment (Product # RP-99080) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641074 |
Product Specific Information
Immunogen sequence:
GDNVTPRENE LWTSLGDSWT RPGLELSPEE GPPYRPEFFS GWEPPVTDPQ SRAWEDPVEK QLQHERRRRQ QSAPQVAVNG HRDLEPE
Antigen sequence identity:
- Mouse: 80%
- Rat: 85%
Target Information
Eps8L1 (EPS8-like 1), also known as DRC3 or EPS8R1, is a 723 amino acid protein that localizes to the cytoplasm and belongs to the Eps8 (epidermal growth factor receptor pathway substrate 8) family. It is expressed in placental tissue and functions to stimulate the guanine exchange activity of Sos1 (son of sevenless homolog 1), promoting the exchange of Ras-bound GDP for GTP. Eps8L1 associates with Actin and may play a role in membrane ruffling and remodeling of the Actin cytoskeleton. Through regulation of protein activation and cytoskeleton dynamics, Eps8L1 is involved in cell growth and differentiation. It contains one SH3 domain and is expressed as four isoforms due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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