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Thermo Fisher Scientific CD16 Monoclonal Antibody (3G8), TRI-COLOR
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Thermo Fisher Scientific CD16 Monoclonal Antibody (3G8), TRI-COLOR

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인간 CD16을 인식하는 마우스 단클론 항체로 TRI-COLOR 형광 표지. Flow Cytometry에 적합하며 다중 표지 실험에 활용 가능. 4°C 암소 보관, 습식 얼음 배송. RRID: AB_10373377.

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pk
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Thermo Fisher Scientific MHCD1606 CD16 Monoclonal Antibody (3G8), TRI-COLOR 0.5 mL pk판매 단위 pk ·
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Thermo Fisher Scientific · Thermo Fisher Scientific CD16 Monoclonal Antibody (3G8), TRI-COLOR

Applications

Flow Cytometry (Flow)

Miscellaneous PubMed (Misc)


Product Specifications

항목 내용
Published species Human
Host / Isotype Mouse / IgG1, kappa
Class Monoclonal
Type Antibody
Clone 3G8
Immunogen Human CD16
Conjugate TRI-COLOR™
Excitation / Emission Max 567 / 671 nm
Form Liquid
Storage conditions 4°C, store in dark
Shipping conditions Wet ice
RRID AB_10373377

Additional Formats

  • Alexa Fluor 700
  • APC
  • FITC
  • Pacific Blue
  • Pacific Orange
  • PE
  • PE-Alexa Fluor 700
  • PE-Texas Red
  • PerCP
  • Custom conjugation available

Product Specific Information

The TRI-COLOR® conjugate is a tandem R-phycoerythrin (PE)-Cy5 conjugate that enables simultaneous multicolor labeling and detection of multiple targets using a single excitation source — the 488 nm line of the argon-ion laser.


Target Information

CD16 encodes a receptor that recognizes the Fc portion of immunoglobulin G and is involved in the clearance of immune complexes, cellular cytotoxicity, and enhancement of viral infections.
The gene FCGR3A shares high similarity with FCGR3B, located on chromosome 1.

  • FCGR3A: Expressed on NK cells as a membrane glycoprotein (transmembrane anchor)
  • FCGR3B: Expressed on PMNs with a phosphatidylinositol (PI) linkage

Mutations in FCGR3A are associated with:

  • Immunodeficiency 20
  • Susceptibility to recurrent viral infections
  • Systemic lupus erythematosus
  • Alloimmune neonatal neutropenia

Alternatively spliced transcript variants encoding different isoforms have been identified.


Analyte Specific Reagent


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