Thermo Fisher Scientific Phospho-Complement C5a Receptor 2 (Ser326, Thr327) Polyclonal Antibody
인산화된 C5a 수용체 2(Ser326, Thr327)를 인식하는 토끼 폴리클로날 항체로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 4°C 단기 보관, -20°C 장기 보관 권장.
- 카탈로그번호
- 7TM0033A
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human C5a2 around the phosphorylation site of Ser326/Thr327 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice (domestic); Dry ice (international) |
Target Information
C5AR2 is an orphan member of the anaphylatoxin receptor family. It is a seven-transmembrane G-protein-coupled receptor containing an N-terminal N-glycosylation site, conserved cysteines, and several potential C-terminal phosphorylation sites. It binds to C5a and C5a-des-Arg, acting as a regulated scavenger receptor with a negative modulatory effect on C5aR-mediated inflammation.
Northern blot analysis indicates co-expression with C5aR in various tissues and cells including neutrophils/macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary, and testis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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