Thermo Fisher Scientific FMN2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human FMN2. Recombinant protein control fragment (Product #RP-106300). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FMN2,uniProtId:Q9NZ56-1,ncbiNodeId:9606,antigenRange:506-616,antigenLength:1722,antigenImageFileName:PA5-65632_FMN2_Q9NZ56-1_Rabbit.svg,antigenImageFileNamePDP:PA5-65632_FMN2_Q9NZ56-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.20 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2664990

Product Specific Information

Immunogen sequence: GVASDSGGGVS PALAAKASGA PAAADGFQNV FTGRTLLEKL FSQQENGPPE EAEKFCSRII AMGLLLPFSD CFREPCNQNA QTNAASFDQD QLYTWAAVSQ PTHSLDYSEG

Highest antigen sequence identity to the following orthologs - mouse 86%, rat 86%.

Target Information

FMN2, a novel formin homology protein of the cappuccino subfamily, is highly conserved between evolutionarily diverse vertebrates. FMN2 bears a high degree of similarity to formin-1 which is the founding member of formin homology proteins. FMN2 plays a crucial role in maintenance of the meiotic spindle. The protein is widely expressed in human fetal brain, adult whole brain, hypothalamus, retina, pancreatic islet and germinal-center B cells. Pathological role of the protein is identified in various tumors like parathyloid tumor, glioblastoma, retinoblastoma and chondrosarcoma. FMN2 mutations are often a cause of unexplained infertility in women. The gene encoding for human FMN2 is localized in the chromosomal region 1q43.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.