Thermo Fisher Scientific FMN2 Polyclonal Antibody
Rabbit polyclonal antibody against human FMN2 단백질. IHC 및 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. 0.20 mg/mL 농도의 액상 형태로 제공되며, 단기 보관은 4°C, 장기 보관은 -20°C 권장. 연구용 전용 제품.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human FMN2. Recombinant protein control fragment (Product # RP-106300) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664990 |
Product Specific Information
Immunogen sequence:
GVASDSGGGVS PALAAKASGA PAAADGFQNV FTGRTLLEKL FSQQENGPPE EAEKFCSRII AMGLLLPFSD CFREPCNQNA QTNAASFDQD QLYTWAAVSQ PTHSLDYSEG
Highest antigen sequence identity to the following orthologs:
- Mouse: 86%
- Rat: 86%
Target Information
FMN2, a novel formin homology protein of the cappuccino subfamily, is highly conserved among vertebrates. FMN2 shows high similarity to formin-1, the founding member of formin homology proteins. It plays a crucial role in maintaining the meiotic spindle and is widely expressed in human fetal brain, adult whole brain, hypothalamus, retina, pancreatic islet, and germinal-center B cells. Pathological roles have been identified in tumors such as parathyroid tumor, glioblastoma, retinoblastoma, and chondrosarcoma. Mutations in FMN2 are associated with unexplained infertility in women. The human FMN2 gene is localized in chromosomal region 1q43.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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