Thermo Fisher Scientific FMNL1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human FMNL1. Recombinant protein control fragment (Product #RP-88597).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641680

Product Specific Information

Immunogen sequence: KNAVLEHMEE LQEQVALLTE RLRDAENESM AKIAELEKQL SQARKELETL RERFSESTAM GASRRPPEPE KAPPAAPTRP SALELKVEEL EEKGLIRILR GPGDAVSIEI LPVAVATPSG GDAPTPGVPT GSPSPDLAPA

Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 81%.

Target Information

The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.