Thermo Fisher Scientific PHF12 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PHF12. Recombinant protein control fragment (Product #RP-93233). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PHF12,uniProtId:Q96QT6-1,ncbiNodeId:9606,antigenRange:805-890,antigenLength:1004,antigenImageFileName:PA5-54400_PHF12_Q96QT6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54400_PHF12_Q96QT6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645480

Product Specific Information

Immunogen sequence: GGAVNMCYRT LYIGTGADMD VCLTNYGHCN YVSGKHACIF YDENTKHYEL LNYSEHGTTV DNVLYSCDFS EKTPPTPPSS IVAKVQ

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Target Information

Acts as a transcriptional repressor. Involved in recruitment of functional SIN3A complexes to DNA. Represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). May also repress transcription in a SIN3A-independent manner through recruitment of functional TLE5 complexes to DNA. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.