Thermo Fisher Scientific ATOH1 Polyclonal Antibody

Thermo Fisher Scientific ATOH1 Polyclonal Antibody

Applications

• Western Blot (WB)

Tested Dilution: 1.0 µg/mL
Publications: -

Product Specifications

Product Specific Information

This target displays homology in the following species:
Cow: 93%; Dog: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 79%; Rat: 93%

Target Information

The Drosophila atonal gene produces a protein with basic helix-loop-helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system.
Mammalian atonal homolog 1 (MATH-1), also known as Atoh1, Ath1, or HATH-1, is a 351 amino acid protein with an atonal-related basic HLH domain.
In mice, expression of MATH-1 occurs by embryonic day 9.5 and initially localizes to the cranial ganglions and the dorsal part of the central nervous system.
Prominent expression is observed in the dorsal part of the CNS but becomes restricted to the external granular layer of the cerebellum by day 18 and is undetectable in the adult nervous system.
MATH-1 may play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.