Thermo Fisher Scientific MED29 Polyclonal Antibody
Rabbit polyclonal antibody against human MED29 for ICC/IF applications. Recognizes recombinant human MED29 with high species identity to mouse and rat. Supplied as liquid form, 0.1 mg/mL in PBS with glycerol. For research use only.
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human MED29. Recombinant protein control fragment (Product # RP-106673) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664962 |
Product Specific Information
Immunogen sequence:
LELCLRLAHEC LSQSCDSAKH SPTLVPTATK PDAVQPDSLP YPQYLAVIKA QISCAKDIHT ALLDCAN
Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 99%
Target Information
In mammalian cells, transcription is regulated in part by high molecular weight co-activating complexes that mediate signals between transcriptional activators and RNA polymerase II (Pol II). The mediator complex functions as a bridge between regulatory proteins and Pol II, thereby regulating Pol II-dependent transcription.
Med29 (mediator complex subunit 29), also known as IXL (intersex-like), is a 200 amino acid nuclear protein and component of the mediator complex. It is widely expressed in embryo and adult tissue and is considered a novel amplification target gene in pancreatic cancer. The gene encoding Med29 maps to human chromosome 19q13.2, which contains over 63 million bases and approximately 1,400 genes, making it the most gene-dense human chromosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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