Thermo Fisher Scientific NPAS2 Monoclonal Antibody (6C9)
Thermo Fisher Scientific의 NPAS2 단클론 항체(6C9)는 인간 NPAS2 단백질을 인식하는 Mouse IgG2a 항체입니다. Western blot 및 ELISA에 적합하며, 액상 형태로 제공됩니다. -20°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6C9 |
| Immunogen | NPAS2 (NP_002509, 646–738 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
NLTTPASTSQ DASQCQPSPD FSHDRQLRLL LSQPIQPMMP GSCDARQPSE VSRTGRQVKY AQSQTVFQNP DAHPANSSSA PMPVLLMGQA VLH
Target Information
Members of the basic helix-loop-helix-PER-ARNT-SIM (bHLH-PAS) family are transcription factors containing a bHLH DNA-binding domain located amino-terminal to a PAS domain.
Neuronal PAS domain protein 2 (NPAS2, also known as PAS4/MOP4) belongs to the bHLH-PAS family and the PAS superfamily. NPAS2 maps to chromosome 2p11.2–2q13 and is primarily expressed in neurons during the first week of postnatal development.
The NPAS2 expression pattern corresponds with learning and memory development and is localized to the frontal association/limbic forebrain pathway. NPAS2 may play a regulatory role in long-term memory maintenance and complex sensory information processing. NPAS2 and MOP3 form a transcriptionally active heterodimer that binds to a CACGTGA-containing DNA element and drives transcription from a linked luciferase reporter gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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