Thermo Fisher Scientific RhoGAP4 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:200–1:500
• Publications: References

Immunocytochemistry (ICC/IF)

• Tested Dilution: 0.25–2 µg/mL
• Publications: References

Product Specifications

Product Specific Information

Immunogen sequence:
DRQTIETEEV NKTLKATLQA LLEVVASDDG DVLDSFQTSP STESLKSTSS DPGSRQAGRR RGQQQETETF YLTKLQEYLS GRSILAKLQA KHEKLQEALQ RGDKEEQEVS WTQYT

• Highest antigen sequence identity to the following orthologs:
  • Mouse: 83%
  • Rat: 88%

Target Information

This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins belonging to the RAS superfamily.
The protein encoded by the orthologous gene in rat is localized to the Golgi complex and can redistribute to microtubules.
The rat protein stimulates the activity of some Rho GTPases in vitro.
Genomic deletions of this gene and a neighboring gene have been found in patients with nephrogenic diabetes insipidus.
Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.