Thermo Fisher Scientific PEG3 Monoclonal Antibody (OTI1F12), TrueMAB
인간 PEG3 단백질(aa 1–364)을 항원으로 제작된 마우스 단클론 항체로, Western blot에 적합합니다. 1 mg/mL 농도의 액상 형태이며, PBS/BSA/glycerol 버퍼에 보관됩니다. 세포 증식 및 p53 매개 세포사멸 연구에 활용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–364 of human PEG3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5′ exons and a common promoter, and both genes are paternally expressed. Alternative splicing connects their shared 5′ exons either with the remaining 4 exons unique to ZIM2 or with the remaining 2 exons unique to PEG3.
In contrast, in other mammals ZIM2 does not undergo imprinting, and in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons.
Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis, and has shown tumor suppressor activity in glioma and ovarian cells. Alternative splicing of PEG3 results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: TA801961_PEG3_Q9GZU2-1_House_mouse.svg, TA801961_PEG3_Q9GZU2-1_House_mouse_PDP.jpeg)
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