Thermo Fisher Scientific TFF3 Monoclonal Antibody (OTI5B2)
TFF3 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot과 IHC(Paraffin) 실험에 적합합니다. 인간 시료에 반응하며, 고순도의 액상 형태로 제공됩니다. 점막 치유 및 세포 이동 관련 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 72–130 of TFF3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725501 |
Target Information
Trefoil peptides are protease-resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds forming the trefoil motif (P-domain) and are clustered on human chromosome 21q22.3.
Trefoil Factor 3 (TFF3) is one of three trefoil peptides secreted by epithelial cells lining mucus membranes in the large and small intestines and lower respiratory tract. TFF3 acts mainly as a disulfide-linked homodimer and may promote cell migration during healing processes. It is involved in the maintenance and repair of the intestinal mucosa.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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