Thermo Fisher Scientific BAG2 Polyclonal Antibody
Thermo Fisher Scientific의 BAG2 Polyclonal Antibody는 인간 BAG2 단백질을 인식하는 Rabbit IgG 기반 항체로, WB, IHC, ICC, IP 등 다양한 응용에 적합합니다. 비결합형 액상 형태로 제공되며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 | - |
| Immunocytochemistry (ICC/IF) | 1:1,000–1:5,000 | - |
| Immunoprecipitation (IP) | 1:50–1:200 | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full-length recombinant human BAG-2 protein (amino acids 1–211) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2718751 |
Target Information
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All BAG proteins share an approximately 45-amino acid BAG domain near the C terminus but differ in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells, binding with high affinity and inhibiting its chaperone activity in a Hip-repressible manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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